Inhibitor of cathepsins B and L; also thought to inhibit calpain. Inhibits lysosomal proteases and interferes with autolysosomal digestion when used in combination with pepstatin A (Cat. Keywords: E 64d, E 64d supplier, lysosomal, proteases, inhibitors, inhibits, cathepsins. Cell-permeable, ethyl ester of Ec. The ester is hydrolyzed by intracellular esterases to produce Ec. Inhibits calpain and cathepsins B, H, and L. Inhibits . Membrane-Permeant Cysteine Protease Inhibitor E64d. S. Eksi,1 B. Czesny,1 G.- J. . or without protease inhibitors, M E64d (Sigma, St Louis, MO), 10 M.

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Flow Cytometry Spectra Viewer. You can save favorites, save cart, check order status and speed through checkout with saved addresses, payment methods and more. View all Cathepsin Inhibitors. The Journal of biological chemistry. See product citations 6. Citations 1 to 6 of 6 total Display: PubMed used Ed, a calpain inhibitor, to determine if calpain protease is e644d possible degradation pathway of ER.


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Ed | CAS | SCBT – Santa Cruz Biotechnology

Rated 5 out of 5 by NZ from This drug exerts its function pretty well This drug exerts its e64c pretty well in autophagy induction. For Research Use Only. Mutants of collagen-specific molecular chaperone Hsp47 causing osteogenesis imperfecta are structurally unstable with weak binding affinity to collagen: Tokyo 35, Abstract.

Mass in vial mg ug ng. A potent inhibitor of thiol protease and cathepsin B, H, and L. Acta, Application s: Ed is a derivative of the membrane permeant Ec sc and acts as a potent inhibitor of thiol protease. Ed is also a cathepsin B, cathepsin H, and cathepsin L siigma.

E-64-d (CAS 88321-09-9)

Our New Product guide highlights over new products added in the second half of Cell culture, Abstract. Please let us know. Click on the entry to view the PubMed entry. Your account has been deactivated. Creating an account with us makes your shopping experience much easier and faster. Certificate sig,a Analysis Catalog Number sc scA. Don’t have an account?


Research shows that Ed can enhance compromised natural killer cells and bactericidal activity of leukocytes. Exercise Can Reprogram the Brain.

The following data is based on the product molecular weight The technical data provided above is for guidance only. Already have an account? Do you know of a great paper that uses E 64d from Tocris?

Submit a review and receive xigma Amazon gift card. Sign-up for new product e-alerts. IHC Hall of Fame. Citations for E 64d Citations are publications that use Tocris products. See how e644d have used Ed. Customized Solutions For Your Workflow. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

Inhibition of calpain in intact platelets by the thiol protease inhibitor Ed: